Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Formaldehyde → Tetrahydro-N-(2-hydroxyethyl)-N-(phosphonomethyl)-3-thiophenamine 1,1-dioxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | Phosphorous acid | HCID 107909 | — |
| 반응물 | 2-[(1,1-Dioxidotetrahydro-3-thienyl)amino]ethanol hydrochloride | HCID 16896370 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Tetrahydro-N-(2-hydroxyethyl)-N-(phosphonomethyl)-3-thiophenamine 1,1-dioxide | HCID 20509043 | 61.9% |
반응 단계
A solution of tetrahydro-N-hydroxymethyl-3-thiophenamine 1,1-dioxide hydrochloride of Example 3 (21.5 parts, 0.1 mole); 90 percent paraformaldehyde (3.7 parts, 0.11 mole); 70 percent aqueous orthophosphorous acid (12.9 parts, 0.11 mole); and water (6.0 parts) was heated at its reflux temperature for 3 hours. The product could not be isolated as a filterable solid due to its hygroscopic nature. The solution containing 61.9 percent of the title compound was used for testing without any further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04374040 |
| 출처 데이터셋 | uspto-grants-1983_02 |
| ORD ID | ord-ff1a9a38b8764641845768319570b3c8 |
| 출처 메모 | uspto-grants-1983_02 |