Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cysteamine Hydrochloride → 2-(Dimethylaminomethyl)-4-(2-aminoethylthiomethyl)thiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cysteamine Hydrochloride | HCID 9082 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | (2-((Dimethylamino)methyl)thiazol-4-yl)methanol | HCID 1838020 | — |
| 반응물 | N-{[4-(chloromethyl)-1,3-thiazol-2-yl]methyl}-N,N-dimethylamine | HCID 1967272 | — |
| 생성물 | 2-(Dimethylaminomethyl)-4-(2-aminoethylthiomethyl)thiazole | HCID 10977318 | — |
반응 단계
When 2-dimethylaminomethyl-4-hydroxymethylthiazole [prepared in Step D] is reacted with thionyl chloride and the resultant 2-dimethylaminomethyl-4-chloromethylthiazole is reacted with an equimolar amount of cysteamine hydrochloride and two equivalents of base according to the general procedure of Example 33, Step D, the title compound is thereby produced.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04374248 |
| 출처 데이터셋 | uspto-grants-1983_02 |
| ORD ID | ord-9b01a9765cd14379bccfde5360abe53e |
| 출처 메모 | uspto-grants-1983_02 |