3-(Dimethylamino)-1-(2-thienyl)-2-propen-1-one → 4-(3-Thienyl)imidazo[1,5-a]pyrimidine-8-carboxamide

HRID 1758795

반응식

HRID 1758795 반응식
[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[N:11]3[CH:12]=[N:13][C:14]([C:15]#[N:16])=[C:10]3[N:9]=[CH:8][CH:7]=2)=[CH:2]1.CN(C)C=CC(C1SC=CC=1)=[O:22]>>[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[N:11]3[CH:12]=[N:13][C:14]([C:15]([NH2:16])=[O:22])=[C:10]3[N:9]=[CH:8][CH:7]=2)=[CH:2]1

참가 물질

3

반응물 2

HCID 6023993-(Dimethylamino)-1-(2-thienyl)-2-propen-1-oneHCID 131173574-(3-Thienyl)imidazo[1,5-a]pyrimidine-8-carbonitrile

생성물 1

HCID 205089424-(3-Thienyl)imidazo[1,5-a]pyrimidine-8-carboxamide

실험 절차

3-Dimethylamino-1-(3-thienyl)-2-propen-1-one (prepared as described in Example 2) can be substituted for 3-dimethylamino-1-(2-thienyl)-2-propen-1-one in the procedure of Example 6, to produce 4-(3-thienyl)imidazo[1,5-a]pyrimidine-8-carboxamide.

출처 및 근거

ORD 기록
ord-31657d16acd941a9b5c6275de50ca61c
출처 데이터셋
uspto-grants-1983_02
특허 번호
US04374988

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