Benzyl Bromide → HCID 13117017, 화합물
반응식
[OH:1][C:2]1[CH:3]=[N:4][O:5][CH:6]=1.[CH2:7](Br)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH2:7]([O:1][C:2]1[CH:3]=[N:4][O:5][CH:6]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1참가 물질
5
반응 조건
- 온도
- 25 °C
실험 절차
A mixture containing 200 mg of 4-hydroxyisoxazole in 10 ml of acetone together with 1.5 equivalents of benzyl bromide and 1.5 equivalents of potassium carbonate is stirred at about 25° C. for five hours. The solid is filtered and the filtrate concentrated to an oil. The crude material is purified by chromatography on silica gel.
후처리
- filtrationThe solid is filtered
- concentrationthe filtrate concentrated to an oil
- customThe crude material is purified by chromatography on silica gel
출처 및 근거
- ORD 기록
- ord-8b06d7e984b2497ea462637c04ad794f
- 출처 데이터셋
- uspto-grants-1982_07
- 특허 번호
- US04339588
반응 노트
불러오는 중…