Potassium Carbonate → HCID 13023013, 화합물
반응식
[Cl:1][C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[OH:14])=[CH:6][CH:7]=1.[CH2:15]([CH:17]1[O:19][CH2:18]1)Br.C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[Cl:1][C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[O:14][CH2:15][CH:17]2[O:19][CH2:18]2)=[CH:6][CH:7]=1참가 물질
5
실험 절차
A mixture of 3-chloro-6-(2-hydroxyphenyl)pyridazine (2.69 g.), epibromohydrin (4.5 ml.), anhydrous potassium carbonate (3.6 g.) and dry butane-2-one (100 ml.) was stirred and heated under reflux for 16 hours. The mixture was filtered and the filtrate was evaporated to dryness and the residue was twice recrystallized from ethanol to give 3-chloro-6-(2-epoxypropoxyphenyl)pyridazine, m.p. 118°-119°.
후처리
- temperatureheated
- temperatureunder reflux for 16 hours
- filtrationThe mixture was filtered
- customthe filtrate was evaporated to dryness
- customthe residue was twice recrystallized from ethanol
출처 및 근거
- ORD 기록
- ord-c7673871e70141e88e1fed2644ed4017
- 출처 데이터셋
- uspto-grants-1982_07
- 특허 번호
- US04340733
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