Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Cyclopropyl-3-oxopropanenitrile → Quinoline-2-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Cyclopropyl-3-oxopropanenitrile | HCID 9812763 | — |
| 반응물 | 2-Amino-4'-fluorobenzophenone | HCID 9837287 | — |
| 생성물 | Quinoline-2-carbonitrile | HCID 74031 | — |
반응 단계
The cyclization reaction step of the present invention is a step of reacting 3-cyclopropyl-3-oxopropanenitrile of the formula (1) with 2-amino-4′-fluorobenzophenone of the formula (2) preferably in the presence of an acid to obtain a quinolinecarbonitrile derivative [2-cyclopropyl-4-(4′-fluorophenyl)quinoline-3-carbonitrile] of the formula (3).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06841681B2 |
| 출처 데이터셋 | uspto-grants-2005_01 |
| ORD ID | ord-fcb79a81fc7d4ba79d80b4b37e899127 |
| 출처 메모 | uspto-grants-2005_01 |