Ammonia → N-(3-Chloropropyl)dibutylamine

HRID 1761259

반응식

HRID 1761259 반응식
N.Cl.[CH2:3]([N:7]([CH2:12][CH2:13][CH2:14][CH3:15])[CH2:8][CH2:9][CH2:10][Cl:11])[CH2:4][CH2:5][CH3:6]>>[CH2:3]([N:7]([CH2:12][CH2:13][CH2:14][CH3:15])[CH2:8][CH2:9][CH2:10][Cl:11])[CH2:4][CH2:5][CH3:6]

참가 물질

3

반응물 2

HCID 222AmmoniaHCID 225950531-Dibutylamino-3-chloropropane hydrochloride

생성물 1

HCID 96084N-(3-Chloropropyl)dibutylamine

실험 절차

288.4 g (3.392 mol) of 20% aqueous ammonia are introduced into a 1 l reactor and then 618 g (1.696 mol) of 1-dibutylamino-3-chloropropane hydrochloride (assay 66.5%) are added over 10 minutes and at ambient temperature (22±2° C.). The mixture is stirred for 45 minutes at ambient temperature and is left to separate by settling for 30 minutes. The lower aqueous phase (pH=11) is removed and the organic phase is washed with 300 ml of deionized water at ambient temperature. Stirring is carried out for 30 minutes, separation by settling is carried out for 30 minutes and the lower aqueous phase (pH=9) is removed.

후처리

  1. waitis left
  2. customto separate
  3. waitby settling for 30 minutes
  4. customThe lower aqueous phase (pH=11) is removed
  5. washthe organic phase is washed with 300 ml of deionized water at ambient temperature
  6. stirringStirring
  7. waitis carried out for 30 minutes
  8. customseparation
  9. waitby settling is carried out for 30 minutes
  10. customthe lower aqueous phase (pH=9) is removed

출처 및 근거

ORD 기록
ord-bb17d9151b89419ead2e5b65b31d58b1
출처 데이터셋
uspto-grants-2005_01
특허 번호
US06846936B2

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