Water → Ipriflavon gamma-cyclodextrin

HRID 1761630노트

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HRID 1761630 반응식
[CH3:1][CH:2]([O:4][C:5]1[CH:6]=[CH:7][C:8]2[C:14](=[O:15])[C:13]([C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:12][O:11][C:9]=2[CH:10]=1)[CH3:3].[CH2:22]([OH:108])[C@H:23]1[O:28][C@@H:27]2[O:29][C@H:30]3[C@H:35]([OH:36])[C@@H:34]([OH:37])[C@@H:33]([O:38][C@H:39]4[C@H:44]([OH:45])[C@@H:43]([OH:46])[C@@H:42]([O:47][C@H:48]5[C@H:53]([OH:54])[C@@H:52]([OH:55])[CH:51]([O:56][CH:57]6[C@H:62]([OH:63])[C@@H:61]([OH:64])[CH:60]([CH:65]7[C@H:70]([OH:71])[C@@H:69]([OH:72])[CH:68]([O:73][C@H:74]8[C@H:79]([OH:80])[C@@H:78]([OH:81])[C@@H:77]([O:82][C@H:83]9[C@H:89]([OH:90])[C@@H:88]([OH:91])[C@@H:86]([O:87][C@H:24]1[C@H:25]([OH:107])[C@H:26]2[OH:106])[O:85][C@@H:84]9[CH2:92][OH:93])[O:76][C@@H:75]8[CH2:94][OH:95])[O:67][C@@H:66]7[CH2:96][OH:97])[O:59][C@@H:58]6[CH2:98][OH:99])[O:50][C@@H:49]5[CH2:100][OH:101])[O:41][C@@H:40]4[CH2:102][OH:103])[O:32][C@@H:31]3[CH2:104][OH:105].O>CC(C)=O>[CH3:3][CH:2]([O:4][C:5]1[CH:6]=[CH:7][C:8]2[C:14](=[O:15])[C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:12][O:11][C:9]=2[CH:10]=1)[CH3:1].[CH2:22]([OH:108])[C@H:23]1[O:28][C@@H:27]2[O:29][C@H:30]3[C@H:35]([OH:36])[C@@H:34]([OH:37])[C@@H:33]([O:38][C@H:39]4[C@H:44]([OH:45])[C@@H:43]([OH:46])[C@@H:42]([O:47][C@H:48]5[C@H:53]([OH:54])[C@@H:52]([OH:55])[CH:51]([O:56][CH:57]6[C@H:62]([OH:63])[C@@H:61]([OH:64])[CH:60]([CH:65]7[C@H:70]([OH:71])[C@@H:69]([OH:72])[CH:68]([O:73][C@H:74]8[C@H:79]([OH:80])[C@@H:78]([OH:81])[C@@H:77]([O:82][C@H:83]9[C@H:89]([OH:90])[C@@H:88]([OH:91])[C@@H:86]([O:87][C@H:24]1[C@H:25]([OH:107])[C@H:26]2[OH:106])[O:85][C@@H:84]9[CH2:92][OH:93])[O:76][C@@H:75]8[CH2:94][OH:95])[O:67][C@@H:66]7[CH2:96][OH:97])[O:59][C@@H:58]6[CH2:98][OH:99])[O:50][C@@H:49]5[CH2:100][OH:101])[O:41][C@@H:40]4[CH2:102][OH:103])[O:32][C@@H:31]3[CH2:104][OH:105]

참가 물질

5

반응물 3

HCID 962WaterHCID 3747IpriflavoneHCID 44431027gamma-Cyclodextrine

생성물 1

HCID 131715936Ipriflavon gamma-cyclodextrin

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

0.5 g (1.78 mmoles) of Ipriflavon were dissolved in 10 ml of acetone in pulg mortar and 4.0 g (3.70 mmoles) of γ-cyclodextrin of 10% by weight moisture content and 2 ml of distilled water were added. The light suspension thus obtained was homogenized with a standing rubbing until the solvent was evaporated. Thereafter the product thus obtained was dried for 24 hours at 60° C. It contains 11.1% of active ingredient and also free γ-cyclodextrin. Molar ratio of Ipriflavon to α-cyclodextrin=1:2.1.

후처리

  1. additionwere added
  2. customThe light suspension thus obtained
  3. customwas evaporated
  4. customThereafter the product thus obtained
  5. customwas dried for 24 hours at 60° C

출처 및 근거

ORD 기록
ord-0d6b7794a7d64a10b75db3989819df1f
출처 데이터셋
uspto-grants-1989_05
특허 번호
US04826963

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