2-(Chloromethyl)furan → 4-(Furan-2-ylmethylsulfanyl)quinazoline

반응식

[SH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][N:3]=1.Cl[CH2:13][C:14]1[O:15][CH:16]=[CH:17][CH:18]=1>>[O:15]1[CH:16]=[CH:17][CH:18]=[C:14]1[CH2:13][S:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][N:3]=1

참가 물질

반응물 2

HCID 2195202-(Chloromethyl)furan

HCID 178527884HCID 178527884, 화합물

생성물 1

HCID 2483484-(Furan-2-ylmethylsulfanyl)quinazoline수율 49.4%

실험 절차

The title compound(3.69 g) was prepared from 4-mercaptoquinazoline(5.0 g) and 2-chloromethylfuran(5.4 g).

출처 및 근거

ORD 기록: ord-372df5dbb28f48ff9b676b2304774745
출처 데이터셋: uspto-grants-1989_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04829069

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