1-Piperazinecarboxaldehyde → HCID 178521668, 화합물
반응식
[O:1]1[CH:11]2[CH:2]1[C:3](=[O:13])[C:4]1[C:9]([C:10]2=[O:12])=[CH:8][CH:7]=[CH:6][CH:5]=1.[N:14]1([CH:20]=[O:21])[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]1>C(O)C>[OH:1][C:11]1[C:10](=[O:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3](=[O:13])[C:2]=1[N:17]1[CH2:18][CH2:19][N:14]([CH:20]=[O:21])[CH2:15][CH2:16]1참가 물질
4
실험 절차
A mixture of 3.48 g of 2,3-epoxy-2,3-dihydro-1,4-naphthoquinone, 2.28 of 1-piperazinecarboxaldehyde and 200 ml of absolute ethanol was stirred for 20 hours, then concentrated to one-half its original volume and refrigerated overnight. The solid was collected and recrystallized from dichloromethane/ethanol, giving 2.65 g of the desired product, mp 200°-203° C.
후처리
- concentrationconcentrated to one-half its original volume and refrigerated overnight
- customThe solid was collected
- customrecrystallized from dichloromethane/ethanol
출처 및 근거
- ORD 기록
- ord-d3f4b4190e224a42b965026a5f41f592
- 출처 데이터셋
- uspto-grants-1989_05
- 특허 번호
- US04829089
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