Ammonia → HCID 86743054, 화합물
반응식
[ClH:1].[C:2]1([CH2:8][O:9][C:10]([NH:12][CH2:13][CH2:14][C:15]2[C:23]3[C:18](=[CH:19][CH:20]=[C:21]([C:24](=[NH:28])OCC)[CH:22]=3)[NH:17][CH:16]=2)=[O:11])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH3:29]>>[OH2:9].[ClH:1].[NH2:29][N:28]=[CH:24][C:21]1[CH:22]=[C:23]2[C:18](=[CH:19][CH:20]=1)[NH:17][CH:16]=[C:15]2[CH2:14][CH2:13][NH:12][C:10](=[O:11])[O:9][CH2:8][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1참가 물질
3
실험 절차
A solution of the product of Stage (i) (0.1 g) in methanolic ammonia solution (25 ml) was stirred at room temperature for 72 h. The mixture was reduced to dryness and the residual oil triturated with a mixture of ethyl acetate and ethanol to give the title compound as a powder (0.06 g), m.p. 248°-250°.
후처리
- customthe residual oil triturated with a mixture of ethyl acetate and ethanol
출처 및 근거
- ORD 기록
- ord-ecfba88c16ab46f99d23743a4de4432f
- 출처 데이터셋
- uspto-grants-1989_05