1-(3-Phenoxyphenyl)ethanol → 2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid

HRID 1762599

반응식

HRID 1762599 반응식
[CH3:1][C:2]1([CH3:16])[CH:4]([CH:5]=[CH:6][C:7]([O:9][CH2:10][CH2:11][CH3:12])=[O:8])[CH:3]1[C:13]([OH:15])=[O:14].O(C1C=C(C(O)C)C=CC=1)[C:18]1C=CC=CC=1>C1C=CC=CC=1>[CH3:16][C:2]1([CH3:1])[CH:4]([CH:5]=[CH:6][C:7]([O:9][CH2:10][CH2:11][CH3:12])=[O:8])[CH:3]1[C:13]([OH:15])=[O:14].[CH3:16][C:2]1([CH3:1])[CH:4]([CH:5]=[CH:6][C:7]([O:9][CH:10]([CH3:11])[CH3:18])=[O:8])[CH:3]1[C:13]([O-:15])=[O:14]

참가 물질

5

반응물 2

HCID 128824191-(3-Phenoxyphenyl)ethanolHCID 545705842,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid

생성물 2

HCID 545705842,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acidHCID 736552712,2-Dimethyl-3-(3-isopropoxy-3-oxo-1-propenyl)-cyclopropane-carboxylate

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

Using the procedure of Example 9, (1R, cis, ΔZ) 2,2-dimethyl-3-(3-isopropoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid and 1-(R) (3-phenoxyphenyl)-ethanol were reacted to obtain 1(R)-(3-phenoxyphenyl)-ethyl (1R, cis, ΔZ) 2,2-dimethyl-3-(3-isopropoxy-3-oxo-1-propenyl)-cyclopropane-carboxylate with a specific rotation of [α]D20 =+140°±2.5° (c=1% in benzene).

후처리

  1. customwere reacted

출처 및 근거

ORD 기록
ord-86fa3193976f477f948960ab966cbfae
출처 데이터셋
uspto-grants-1989_05
특허 번호
US04833163

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