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[CH2:1]([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[C:12]([C:15](=[O:18])[CH2:16][Cl:17])[CH:11]=[CH:10][C:9]=2[OH:19])=[O:5])[CH3:2].[CH2:20]([O:22][C:23](=[O:36])[CH2:24][C:25]([NH:28][CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)([CH3:27])[CH3:26])[CH3:21]>>[ClH:17].[CH2:1]([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[C:12]([C:15](=[O:18])[CH2:16][N:28]([CH2:29][C:30]1[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=1)[C:25]([CH3:26])([CH3:27])[CH2:24][C:23]([O:22][CH2:20][CH3:21])=[O:36])[CH:11]=[CH:10][C:9]=2[OH:19])=[O:5])[CH3:2]참가 물질
3
실험 절차
Under the conditions of Example 28, 2.57 g of 4-chloroacetyl-7-hydroxyindole-2-carboxylic acid ethyl ester is reacted with 2.35 g of 3-benzylamino-3-methylbutyric acid ethyl ester and worked up, yielding 0.75 g of 4-[N-benzyl-N-(2-ethoxycarbonyl-1,1-dimethylethyl)aminoacetyl]-7-hydroxyindole-2-carboxylic acid ethyl ester hydrochloride, decomposition point 210°-212° C.
출처 및 근거
- ORD 기록
- ord-97730f51818f4c69874a30141c7f4ad7
- 출처 데이터셋
- uspto-grants-1989_05
- 특허 번호
- US04835175
연결된 노트
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