5-Chloro-2-methoxybenzoyl chloride → HCID 20304389, 화합물

반응식

Cl.[NH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][CH2:11][C:12]([O:14]CC)=[O:13])=[CH:6][CH:5]=1.[Cl:17][C:18]1[CH:19]=[CH:20][C:21]([O:27][CH3:28])=[C:22]([CH:26]=1)[C:23](Cl)=[O:24]>>[Cl:17][C:18]1[CH:19]=[CH:20][C:21]([O:27][CH3:28])=[C:22]([CH:26]=1)[C:23]([NH:2][CH2:3][C:4]1[CH:5]=[CH:6][C:7]([CH2:10][CH2:11][C:12]([OH:14])=[O:13])=[CH:8][CH:9]=1)=[O:24]

참가 물질

반응물 2

HCID 123841765-Chloro-2-methoxybenzoyl chloride

HCID 20304428Ethyl 3-[4-(aminomethyl)phenyl]propanoate--hydrogen chloride (1/1)

생성물 1

HCID 20304389HCID 20304389, 화합물

실험 절차

By reaction of ethyl β-[4-(aminomethyl)-phenyl]-propionate hydrochloride (m.p. 192°-193° C.) with 5-chloro-2-methoxybenzoyl chloride, there is obtained β-[4-(5-chloro-2-methoxybenzamidomethyl)-phenyl]-propionic acid; m.p. 152°-153° C., after recrystallization from isopropanol.

출처 및 근거

ORD 기록: ord-65cdcfd722574cdf819d24f87418b942
출처 데이터셋: uspto-grants-1978_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04113871

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