Quinoline → 3-Buten-2-ol, 1,1-dimethoxy-2-methyl-

HRID 1764561노트

반응식

HRID 1764561 반응식
[CH3:1][O:2][CH:3]([O:9][CH3:10])[C:4]([CH3:8])([OH:7])[C:5]#[CH:6].N1C2C(=CC=CC=2)C=CC=1.[H][H]>[Pd]>[CH3:1][O:2][CH:3]([O:9][CH3:10])[C:4]([CH3:8])([OH:7])[CH:5]=[CH2:6]

참가 물질

5

반응물 3

HCID 7047QuinolineHCID 128752274,4-Dimethoxy-3-methyl-but-1-yn-3-olHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 110080503-Buten-2-ol, 1,1-dimethoxy-2-methyl-

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

198 G. of 4,4-dimethoxy-3-methyl-but-1-yn-3-ol are dissolved in 960 ml. of high-boiling petroleum ether and, after the addition of 19.35% palladium catalyst and 19.3 g. of quinoline, hydrogenated under normal conditions. After the uptake of 33.5 l. of hydrogen, the hydrogenation is stopped. The catalyst is filtered off. The filtrate is evaporated under reduced pressure. The remaining 4,4-dimethoxy-3-methyl-but-1-en-3-ol boils, after rectification, at 70°-72° C./18 mm Hg.

후처리

  1. filtrationThe catalyst is filtered off
  2. customThe filtrate is evaporated under reduced pressure
  3. customat 70°-72° C.

출처 및 근거

ORD 기록
ord-e76f93dd4ca34e539ed05c2321c99da9
출처 데이터셋
uspto-grants-1978_09
특허 번호
US04116975

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