HCID 22768929, 화합물 → HCID 22768927, 화합물
반응식
[CH3:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([N+:14]([O-])=O)[CH:9]=2)=[N:6][N:5]2[CH:17]=[N:18][N:19]=[C:4]2[CH:3]=1>[Pt]=O.C(O)C>[NH2:14][C:10]1[CH:9]=[C:8]([C:7]2[C:2]([CH3:1])=[CH:3][C:4]3[N:5]([CH:17]=[N:18][N:19]=3)[N:6]=2)[CH:13]=[CH:12][CH:11]=1참가 물질
4
실험 절차
A mixture comprising 2.28 g. of 7-methyl-6-(m-nitrophenyl)-1,2,4-triazolo[4,3-b]pyridazine (prepared as described in Example 4), 100 ml. of ethyl alcohol and a catalytic amount of platinum oxide is shaken in a Parr shaker under 40 pounds of hydrogen pressure for 11/2 hours. The reaction mixture is filtered free of catalyst and the filtrate is concentrated to afford the product of the example as a yellow solid, m.p. 182°-186° C.
후처리
- filtrationThe reaction mixture is filtered free of catalyst
- concentrationthe filtrate is concentrated
- customto afford the product of the example as a yellow solid, m.p. 182°-186° C.
출처 및 근거
- ORD 기록
- ord-4157ddd3ab7642d4ad9633cde00ea024
- 출처 데이터셋
- uspto-grants-1978_09
- 특허 번호
- US04117130
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