돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1766757생성일: 2026년 10월 27일

(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine → {4-[6-Amino-5-(2,6-difluoro-benzyloxy)-pyridin-3-yl]-phenyl}-[(2S)-2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl]-methanone

https://huagongshe.com/reaction/1766757

반응식

참여 물질

역할이름HCID투입량
반응물(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidineHCID 853152—
반응물4-[6-Amino-5-(2,6-difluoro-benzyloxy)-pyridin-3-yl]-benzoic acidHCID 21111235—
생성물{4-[6-Amino-5-(2,6-difluoro-benzyloxy)-pyridin-3-yl]-phenyl}-[(2S)-2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl]-methanoneHCID 58885981—

반응 단계

{4-[6-Amino-5-(2,6-difluoro-benzyloxy)-pyridin-3-yl]-phenyl}-[(2S)-2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl]-methanone was prepared from 4-[6-amino-5-(2,6-difluoro-benzyloxy)-pyridin-3-yl]-benzoic acid and (2S)-2-pyrrolidin-1-ylmethyl-pyrrolidine following procedure 4.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07230098B2
출처 데이터셋uspto-grants-2007_06
ORD IDord-9d06fc63f4474d6bbe797af592a76a2f
출처 메모uspto-grants-2007_06