Acetyl chloride → 2-Acetamidophenylboronic acid

반응식

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[B:8]([OH:10])[OH:9].C(N(CC)CC)C.[C:18](Cl)(=[O:20])[CH3:19]>>[C:18]([NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[B:8]([OH:10])[OH:9])(=[O:20])[CH3:19]

참가 물질

반응물 3

HCID 6367Acetyl chloride

HCID 8471Triethylamine

HCID 2773216(2-Aminophenyl)boronic acid

생성물 1

HCID 27377892-Acetamidophenylboronic acid수율 63.5%

실험 절차

A mixture of 2-aminophenylboronic acid (900 mg; 6.6 mmol), triethylamine (0.57 ml; 7 mmol) and acetylchloride (0.5 ml; 7 mmol) was stirred at rt. for 1 h. The reaction mixture was evaporated to dryness, stirred with H2O and filtered to give 750 mg (63%) product.