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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1768142생성일: 2026년 10월 26일

6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione → (RS)-2-oxo-1-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-pyrrolidine-3-carboxylic acid

https://huagongshe.com/reaction/1768142

반응식

참여 물질

역할이름HCID투입량
반응물6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dioneHCID 79720—
반응물4-(4-Trifluoromethyl-benzyloxy)-phenylamineHCID 22137889—
생성물(RS)-2-oxo-1-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-pyrrolidine-3-carboxylic acidHCID 23614753—

반응 단계

The title compound is prepared in analogy to Example 3c) from 4-(4-trifluoromethyl-benzyloxy)-phenylamine and 6,6-dimethyl-5,7-dioxa-spiro[2,5]octane-4,8-dione. Yield: 37% of a colorless solid. MS: m/e=380.1 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07235581B2
출처 데이터셋uspto-grants-2007_06
ORD IDord-e82aceb8b5e7496b8dca613177d52431
출처 메모uspto-grants-2007_06