Acetic acid, 2-(2-formylphenoxy)- → HCID 18948980, 화합물

HRID 1768607노트

반응식

HRID 1768607 반응식
[CH:1]([C:3]1[CH:13]=[CH:12][CH:11]=[CH:10][C:4]=1[O:5][CH2:6][C:7]([OH:9])=[O:8])=O.[NH2:14]/[C:15](/[CH3:21])=[CH:16]\[C:17]([O:19][CH3:20])=[O:18]>CO>[CH3:20][O:19][C:17]([C:16]1[CH:1]([C:3]2[CH:13]=[CH:12][CH:11]=[CH:10][C:4]=2[O:5][CH2:6][C:7]([OH:9])=[O:8])[C:16]([C:17]([O:19][CH3:20])=[O:18])=[C:15]([CH3:21])[NH:14][C:15]=1[CH3:21])=[O:18]

참가 물질

4

반응물 2

HCID 46533Acetic acid, 2-(2-formylphenoxy)-HCID 643918Methyl 3-aminocrotonate

생성물 1

HCID 18948980HCID 18948980, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A solution of 5 g of 2-formylphenoxyacetic acid and 6.4 g of methyl 3-aminocrotonate in methanol was refluxed for 24 hours and evaporated. The residue was dissolved in a solution of sodium carbonate in water. This solution was washed twice with ethyl acetate and acidified to pH 2 with dilute hydrochloric acid, after which the solution was again extracted with ethyl acetate. The organic layer was dried over magnesium sulfate and evaporated. The residue was crystallized from ethyl acetate/petroleum ether 60-80.

후처리

  1. customevaporated
  2. dissolutionThe residue was dissolved in a solution of sodium carbonate in water
  3. washThis solution was washed twice with ethyl acetate
  4. extractionafter which the solution was again extracted with ethyl acetate
  5. dry with materialThe organic layer was dried over magnesium sulfate
  6. customevaporated
  7. customThe residue was crystallized from ethyl acetate/petroleum ether 60-80

출처 및 근거

ORD 기록
ord-230fc64097a04856936656f727631c59
출처 데이터셋
uspto-grants-1995_01
특허 번호
US05378718

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