Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-Benzoyl-4,5-dimethoxybenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ammonium Chloride | HCID 25517 | — |
| 반응물 | 5,6-Dimethoxy-1,3-dihydro-2-benzofuran-1,3-dione | HCID 610356 | — |
| 반응물 | HCID 178478979 | HCID 178478979 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-Benzoyl-4,5-dimethoxybenzoic acid | HCID 19957159 | 74.9% |
반응 단계
Thirty grams (0.14 mole) of 4,5-dimethoxyphthalic anhydride was suspended in 300 mL of THF and 87 mL (0.17 mole) of phenylmagnesium chloride in THF was added over two hours. The reaction was stirred at room temperature for 14 hours, refluxed for two hours, cooled and poured into saturated ammonium chloride. The mixture was made acidic with 6N HCl, extracted into chloroform, dried over magnesium sulfate, concentrated to provide 30 g of 2-benzoyl-4,5-dimethoxybenzoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05380721 |
| 출처 데이터셋 | uspto-grants-1995_01 |
| ORD ID | ord-1f0bae2485794e7ead1b1aede4b420fb |
| 출처 메모 | uspto-grants-1995_01 |