4-Hydroxybenzaldehyde → 4-(1-Methylbutyloxy)benzaldehyde
반응식
[OH:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.[CH3:10][C@H:11](OS(C1C=CC(C)=CC=1)(=O)=O)[CH2:12][CH2:13][CH3:14].C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH3:10][CH:11]([O:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1)[CH2:12][CH2:13][CH3:14]참가 물질
5
실험 절차
40 g of 4-hydroxybenzaldehyde, 80 g of (S) -1-methylbutyl-p-toluene sulfonate and 46 g of potassium carbonate were refluxed in acetone for 12 hours, insoluble matters were removed from the reaction solution while the reaction solution was hot, and the solvent used was distilled out. The residue was purified by column chromatography to obtain 4-(1-methylbutyloxy) benzaldehyde (30).
후처리
- custominsoluble matters were removed from the reaction solution while the reaction solution
- distillationthe solvent used was distilled out
- customThe residue was purified by column chromatography
출처 및 근거
- ORD 기록
- ord-b3fed3d952244fd99704b2b0c742af53
- 출처 데이터셋
- uspto-grants-1995_01
- 특허 번호
- US05380915
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