Ethanol → Ethoxycarbonylpropyleneurea
반응식
[O:1]([C:8]([CH2:10][CH:11]([NH:13][C:14]([NH2:16])=[O:15])[CH3:12])=[O:9])[C:2]1C=CC=C[CH:3]=1.C(O)C.C([O-])(=O)CCCCCCCCCCC.C([O-])(=O)CCCCCCCCCCC.C([Sn+2]CCCC)CCC>O1CCOCC1>[CH2:2]([O:1][C:8]([CH2:10][CH:11]([NH:13][C:14]([NH2:16])=[O:15])[CH3:12])=[O:9])[CH3:3]참가 물질
5
실험 절차
Phenoxycarbonylpropyleneurea of 1 g (4.5 mmol) and ethanol of 10 g (21.7 mmol) were dissolved in dioxane of 20 ml by heating. Dibutyltin dilaurate of 10 mg (1%) was added to the resulting solution and the resulting mixture was heated for 5 hours with stirring. After confirming the completion of the reaction by the thin layer chromatography, the reaction product was concentrated and the resulting crude crystals were washed with ether to obtain the aimed substance of 567 mg (80%).
후처리
- temperatureby heating
- temperaturethe resulting mixture was heated for 5 hours
- customthe completion of the reaction by the thin layer chromatography
- concentrationthe reaction product was concentrated
- washthe resulting crude crystals were washed with ether
- customto obtain the aimed substance of 567 mg (80%)
출처 및 근거
- ORD 기록
- ord-158e7b3fdb944bb99035cafc6a3d4f05
- 출처 데이터셋
- uspto-grants-1995_01
- 특허 번호
- US05385985
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