4-[(Furan-2-ylmethyl)sulfamoyl]benzoic acid → 4-(N-(furan-2-ylmethyl)-N-(3-methoxybenzyl)sulfamoyl)benzoic acid

HRID 1770437

반응식

HRID 1770437 반응식
Br[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9][CH3:10])[CH:4]=1.[O:11]1[CH:15]=[CH:14][CH:13]=[C:12]1[CH2:16][NH:17][S:18]([C:21]1[CH:29]=[CH:28][C:24]([C:25]([OH:27])=[O:26])=[CH:23][CH:22]=1)(=[O:20])=[O:19]>>[O:11]1[CH:15]=[CH:14][CH:13]=[C:12]1[CH2:16][N:17]([CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9][CH3:10])[CH:4]=1)[S:18]([C:21]1[CH:29]=[CH:28][C:24]([C:25]([OH:27])=[O:26])=[CH:23][CH:22]=1)(=[O:20])=[O:19]

참가 물질

3

반응물 2

HCID 6815254-[(Furan-2-ylmethyl)sulfamoyl]benzoic acidHCID 40672073-Methoxybenzyl bromide

생성물 1

HCID 238577624-(N-(furan-2-ylmethyl)-N-(3-methoxybenzyl)sulfamoyl)benzoic acid수율 35%

실험 절차

Prepared as in Example 5-5 from 1-(bromomethyl)-3-methoxybenzene and 4-(N-(furan-2-ylmethyl)sulfamoyl)benzoic acid (Example 5-2b). Yield 35%. MS M+H calculated 402.3. Found 402.0.

출처 및 근거

ORD 기록
ord-e16a65793b9b409d9e2b1ccdb199ae2e
출처 데이터셋
uspto-grants-2016_02
특허 번호
US09247759B2

연결된 노트

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