Methyl D-alaninate hydrochloride → HCID 59524381, 화합물

반응식

[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH:12]=O)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].Cl.[NH2:18][C@H:19]([CH3:24])[C:20]([O:22][CH3:23])=[O:21]>>[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH2:12][NH:18][C@H:19]([CH3:24])[C:20]([O:22][CH3:23])=[O:21])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

참가 물질

반응물 2

HCID 11182647Methyl D-alaninate hydrochloride

HCID 112071113-(t-Butyldimethylsilyloxy)benzaldehyde

생성물 1

HCID 59524381HCID 59524381, 화합물수율 82%

실험 절차

Prepared as in Example 12-1b from 3-(tert-butyldimethylsilyloxy)benzaldehyde (Example 12-1c) and (R)-methyl 2-aminopropanoate hydrochloride. Yield 82%, colorless liquid. MS 324 (MH+).

출처 및 근거

ORD 기록: ord-973ad08f3df3462389d00a13f6ff2c41
출처 데이터셋: uspto-grants-2016_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09247759B2

반응 노트

불러오는 중…