3-(t-Butyldimethylsilyloxy)benzaldehyde → HCID 59524397, 화합물

반응식

[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH:12]=O)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].Cl.[NH2:18][C:19]([CH3:26])([CH2:24][OH:25])[C:20]([O:22][CH3:23])=[O:21]>>[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH2:12][NH:18][C:19]([CH3:26])([CH2:24][OH:25])[C:20]([O:22][CH3:23])=[O:21])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

참가 물질

반응물 2

HCID 112071113-(t-Butyldimethylsilyloxy)benzaldehyde

HCID 13221872Methyl 2-amino-3-hydroxy-2-methylpropanoate hydrochloride

생성물 1

HCID 59524397HCID 59524397, 화합물수율 97%

실험 절차

Prepare as in Example 12-9c from 3-(tert-butyldimethylsilyloxy)benzaldehyde (Example 12-1c) and methyl 2-amino-3-hydroxy-2-methylpropanoate hydrochloride. Yield 97%, yellowish oil. MS 354 (MH+).

출처 및 근거

ORD 기록: ord-0c227b337a5b434390bdaa69cc731ff4
출처 데이터셋: uspto-grants-2016_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09247759B2

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