Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 7-Carboxyheptyl 5-amino-4-oxopentanoate hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 7-(benzyloxycarbonyl)heptyl 5-(Cbz-amino)-4-oxopentanoate | HCID 90034499 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 7-Carboxyheptyl 5-amino-4-oxopentanoate hydrochloride | HCID 90034497 | 70% |
반응 단계
This compound was prepared from the product of 10b (0.70 g; 1.4 mmol), 12 M HCl (0.12 mL; 1.4 mmol), 10% Pd/C (100 mg), hydrogen gas, and 2-propanol (25 mL) using the procedure in Example 8d. 0.30 g (70%) product was obtained (white solid).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09249086B2 |
| 출처 데이터셋 | uspto-grants-2016_02 |
| ORD ID | ord-887101cd9ad64a7a8858326e84974336 |
| 출처 메모 | uspto-grants-2016_02 |