HCID 89474285, 화합물 → HCID 89462331, 화합물
반응식
[F:1][C:2]1[C:7]([C:8]([C:10]2[CH:11]=[C:12]3[C:17](=[CH:18][CH:19]=2)[N:16]=[CH:15][CH:14]=[N:13]3)=[O:9])=[C:6]([F:20])[CH:5]=[CH:4][C:3]=1[NH:21]C(=O)OC(C)(C)C>CO>[NH2:21][C:3]1[C:2]([F:1])=[C:7]([C:8]([C:10]2[CH:11]=[C:12]3[C:17](=[CH:18][CH:19]=2)[N:16]=[CH:15][CH:14]=[N:13]3)=[O:9])[C:6]([F:20])=[CH:5][CH:4]=1참가 물질
3
시약·촉매·용매 1
실험 절차
A solution of tert-butyl (2,4-difluoro-3-(quinoxaline-6-carbonyl)phenyl)carbamate (600 mg, 1.56 mmol, 1 eq.) in HO/MeOH (6 N, 50 mL) was stirred at rt for 3 h, then concentrated to provide crude (3-amino-2,6-difluorophenyl) (quinoxalin-6-yl)methanone which was used in the next step without further purification.
후처리
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-77baba7c865a4f68837d3ec031a4a942
- 출처 데이터셋
- uspto-grants-2016_02
- 특허 번호
- US09249110B2
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