4-(Methoxymethyl)phenylglyoxal → 5-[4-(Methoxymethyl)phenyl]-3-(methylsulfanyl)-1,2,4-triazine

HRID 1771298노트

반응식

[NH:1]([C:3]([S:5][CH3:6])=[NH:4])[NH2:2].[CH3:7][O:8][CH2:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]([CH:18]=O)=O)=[CH:12][CH:11]=1>>[CH3:7][O:8][CH2:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[N:4]=[C:3]([S:5][CH3:6])[N:1]=[N:2][CH:18]=2)=[CH:12][CH:11]=1

참가 물질

반응물 2

HCID 543061534-(Methoxymethyl)phenylglyoxal

HCID 178504051Methyl hydrazinecarbimidothioate

생성물 1

HCID 673649815-[4-(Methoxymethyl)phenyl]-3-(methylsulfanyl)-1,2,4-triazine수율 72%

실험 절차

5-[4-(methoxymethyl)phenyl]-3-(methylsulfanyl)-1,2,4-triazine (4.0 g, 72%) was prepared from methyl hydrazinecarbimidothioate (7.33 g, 31.46 mmol) and 4-(methoxymethyl)phenylglyoxal (4 g, 22.47 mmol) according to the general procedure of Preparation 2.

후처리

customaccording to the general procedure of Preparation 2

출처 및 근거

ORD 기록: ord-d7b89ad2bafb4fe9a369233c4595fdbb
출처 데이터셋: uspto-grants-2016_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09249130B2

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