HCID 86676113, 화합물 → 3-(Methylsulfanyl)-5-(3-chloro-5-fluorophenyl)-1,2,4-triazine

HRID 1771300노트

반응식

HRID 1771300 반응식
[NH:1]([C:3]([S:5][CH3:6])=[NH:4])[NH2:2].[Cl:7][C:8]1[CH:9]=[C:10]([C:15](=O)[CH:16]=O)[CH:11]=[C:12]([F:14])[CH:13]=1>>[CH3:6][S:5][C:3]1[N:1]=[N:2][CH:16]=[C:15]([C:10]2[CH:11]=[C:12]([F:14])[CH:13]=[C:8]([Cl:7])[CH:9]=2)[N:4]=1

참가 물질

3

반응물 2

HCID 86676113HCID 86676113, 화합물HCID 178504051Methyl hydrazinecarbimidothioate

생성물 1

HCID 673657063-(Methylsulfanyl)-5-(3-chloro-5-fluorophenyl)-1,2,4-triazine수율 38.6%

실험 절차

3-(methylsulfanyl)-5-(3-chloro-5-fluorophenyl)-1,2,4-triazine (16 g, 38.4%) was prepared from methyl hydrazinecarbimidothioate (25.5 g, 243 mmol) and 2-(3-chloro-5-fluorophenyl)-2-oxoacetaldehyde (30 g, 162 mmol) according to the general procedure of Preparation 2.

후처리

  1. customaccording to the general procedure of Preparation 2

출처 및 근거

ORD 기록
ord-8900fa1218aa4fecae48ea841c334aef
출처 데이터셋
uspto-grants-2016_02
특허 번호
US09249130B2

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