Cesium carbonate → Methyl 2-tert-Butyl-4-((2-((tert-butyldimethylsilyloxy)methyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylamino)methyl)thiazole-5-carboxylate

반응식

Br[CH2:2][C:3]1[N:4]=[C:5]([C:12]([CH3:15])([CH3:14])[CH3:13])[S:6][C:7]=1[C:8]([O:10][CH3:11])=[O:9].[Si:16]([O:23][CH2:24][C:25]1[C:30]([B:31]2[O:35][C:34]([CH3:37])([CH3:36])[C:33]([CH3:39])([CH3:38])[O:32]2)=[CH:29][CH:28]=[CH:27][C:26]=1[NH2:40])([C:19]([CH3:22])([CH3:21])[CH3:20])([CH3:18])[CH3:17].C(=O)([O-])[O-].[Cs+].[Cs+]>C(#N)C>[C:12]([C:5]1[S:6][C:7]([C:8]([O:10][CH3:11])=[O:9])=[C:3]([CH2:2][NH:40][C:26]2[CH:27]=[CH:28][CH:29]=[C:30]([B:31]3[O:35][C:34]([CH3:37])([CH3:36])[C:33]([CH3:38])([CH3:39])[O:32]3)[C:25]=2[CH2:24][O:23][Si:16]([C:19]([CH3:22])([CH3:21])[CH3:20])([CH3:18])[CH3:17])[N:4]=1)([CH3:15])([CH3:14])[CH3:13]