2-(Azetidin-3-yl)quinoline → HCID 117728045, 화합물

반응식

Cl[C:2]1[N:3]=[C:4]2[C:9]([N:10]3[CH2:15][CH2:14][O:13][CH2:12][CH2:11]3)=[N:8][CH:7]=[CH:6][N:5]2[CH:16]=1.[NH:17]1[CH2:20][CH:19]([C:21]2[CH:30]=[CH:29][C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[N:22]=2)[CH2:18]1>>[N:22]1[C:23]2[C:28](=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:29]=[CH:30][C:21]=1[CH:19]1[CH2:18][N:17]([C:2]2[N:3]=[C:4]3[C:9]([N:10]4[CH2:15][CH2:14][O:13][CH2:12][CH2:11]4)=[N:8][CH:7]=[CH:6][N:5]3[CH:16]=2)[CH2:20]1

참가 물질

반응물 2

HCID 585484432-(Azetidin-3-yl)quinoline

HCID 117727948HCID 117727948, 화합물

생성물 1

HCID 117728045HCID 117728045, 화합물

실험 절차

Compound 25a was prepared from compound 24a and compound 24d using the procedure described in Example 24, Step E. Mass Spectrum (LCMS, ESI pos.) Calcd. For C22H22N6O: 387.2 (M+H). Found 387.2.

출처 및 근거

ORD 기록: ord-09c26c05810c402699ecb02a17ee2af7
출처 데이터셋: uspto-grants-2016_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09249163B2

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