Sodium ethoxide → HCID 89826007, 화합물
반응식
[Br:1][C:2]1[CH:7]=[C:6]([N+]([O-])=O)[CH:5]=[C:4]([CH3:11])[N+:3]=1[O-:12].[O-:13][CH2:14][CH3:15].[Na+]>C(O)C>[Br:1][C:2]1[CH:7]=[C:6]([O:13][CH2:14][CH3:15])[CH:5]=[C:4]([CH3:11])[N+:3]=1[O-:12]참가 물질
4
실험 절차
2-Bromo-6-methyl-4-nitro-pyridine 1-oxide (1 g, 4.3 mmol) was dissolved in ethanol (anhydrous, 50 ml), and sodium ethoxide (21% in ethanol, 1.4 ml, 4.3 mmol) was added dropwise with stirring. The mixture was stirred at room temperature overnight, concentrated under reduced pressure, the residue was taken up in DCM (50 ml), the mixture was washed with water (50 ml), dried (sodium sulfate) and concentrated under reduced pressure to yield 0.84 g of brown yellow crystals (3.6 mmol, 84%).
후처리
- stirringThe mixture was stirred at room temperature overnight
- concentrationconcentrated under reduced pressure
- washthe mixture was washed with water (50 ml)
- dry with materialdried (sodium sulfate)
- concentrationconcentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-e5ae67b001544e7cbbf79b18a5c49923
- 출처 데이터셋
- uspto-grants-2016_02
- 특허 번호
- US09260441B2
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