3-(4-Chlorophenyl)-1-Methyl-1H-Pyrazol-5-Amine → 4-chloro-3-(4-chlorophenyl)-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine

HRID 1775519

반응식

HRID 1775519 반응식
[Cl:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[N:6][N:5]=[C:4]2[N:14]([CH3:24])[N:15]=[C:16](C3C=CC=CC=3Cl)[C:3]=12.[Cl:25][C:26]1[CH:31]=[CH:30][C:29](C2C=C(N)N(C)N=2)=[CH:28][CH:27]=1>>[Cl:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[N:6][N:5]=[C:4]2[N:14]([CH3:24])[N:15]=[C:16]([C:29]3[CH:30]=[CH:31][C:26]([Cl:25])=[CH:27][CH:28]=3)[C:3]=12

참가 물질

3

반응물 2

HCID 27353043-(4-Chlorophenyl)-1-Methyl-1H-Pyrazol-5-AmineHCID 665764824-chloro-3-(2-chlorophenyl)-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine

생성물 1

HCID 665768914-chloro-3-(4-chlorophenyl)-1-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine

실험 절차

Compound 26 was synthesised following similar procedures outlined in Example 1 (Compound 37), starting from Step 2 using 3-(4-chlorophenyl)-1-methyl-1H-pyrazol-5-amine instead of 3-(2-chlorophenyl)-1-methyl-1H-pyrazol-5-amine.

출처 및 근거

ORD 기록
ord-610687ba0f124faa83eeb457d0b2fe50
출처 데이터셋
uspto-grants-2016_02
특허 번호
US09260381B2

연결된 노트

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