Methanol → 2-(3-(4-Amino-6-chloropyridin-3-yl)prop-2-ynyl)-6-(thiophen-2-yl)pyridazin-3(2H)-one

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[CH2:8]([C:9]#[CH:10])[n:11]1[n:12][c:13](-[c:18]2[s:19][cH:20][cH:21][cH:22]2)[cH:14][cH:15][c:16]1=[O:17].[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:32][OH:33].[CH3:34][C:35]#[N:36].[Cl:23][c:24]1[n:25][cH:26][c:27]([I:31])[c:28]([NH2:30])[cH:29]1.[Cl:37][CH2:38][Cl:39]>>[CH2:8]([C:9]#[C:10][c:27]1[cH:26][n:25][c:24]([Cl:23])[cH:29][c:28]1[NH2:30])[n:11]1[n:12][c:13](-[c:18]2[s:19][cH:20][cH:21][cH:22]2)[cH:14][cH:15][c:16]1=[O:17]