Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Alcohol → HCID 52463841, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Alcohol | HCID 244 | — |
| 반응물 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 반응물 | (3,5-Dimethyl-1H-pyrazol-1-yl)acetic acid | HCID 572875 | — |
| 촉매 | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | HCID 52463841 | HCID 52463841 | — |
반응 단계
A mixture of (3,5-dimethyl-1H-pyrazol-1-yl)acetic acid (600 mg), benzyl alcohol (0.402 mL), DMAP (194 mg) and DCC (802 mg) in MeCN (40 mL) was stirred at RT overnight. The suspension was filtered off and the resulting solution was evaporated to dryness. The residue was purified by CC (Hept/EA 7/3) to afford benzyl 2-(3,5-dimethyl-1H-pyrazol-1-yl)acetate (460 mg, white solid). LC-MS (B): tR=0.80 min; [M+H]+: 245.18.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09266876B2 |
| 출처 데이터셋 | uspto-grants-2016_02 |
| ORD ID | ord-bd5d153c9de04fad9880e8f06258083d |
| 출처 메모 | uspto-grants-2016_02 |