HCID 11602119, 화합물 → HCID 76285147, 화합물
반응식
[F:1][C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([O:10][CH3:11])=[C:4]([F:12])[C:3]=1[C:13]1[N:18]=[CH:17][C:16]2[C:19](I)=[N:20][N:21](C3CCCCO3)[C:15]=2[CH:14]=1.CC1(C)C(C)(C)OB([C:37]2[CH:38]=[CH:39][C:40]3[O:44][C:43]([C:45]([O:47][CH2:48]C)=[O:46])=[CH:42][C:41]=3[CH:50]=2)O1>>[F:1][C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([O:10][CH3:11])=[C:4]([F:12])[C:3]=1[C:13]1[N:18]=[CH:17][C:16]2[C:19]([C:37]3[CH:38]=[CH:39][C:40]4[O:44][C:43]([C:45]([O:47][CH3:48])=[O:46])=[CH:42][C:41]=4[CH:50]=3)=[N:20][NH:21][C:15]=2[CH:14]=1참가 물질
3
실험 절차
This compound was prepared by using procedures analogous to those described for the synthesis of Example 52, Step 8 starting from 6-(2,6-difluoro-3,5-dimethoxyphenyl)-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[4,3-c]pyridine (9 mg, 0.02 mmol; from step 6) and ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran-2-carboxylate. LCMS (M+H)+: m/z=466.2.
후처리
- customThis compound was prepared