Potassium Carbonate → HCID 54349857, 화합물

HRID 1780005노트

반응식

HRID 1780005 반응식
[CH3:1][C:2]([NH:11][C:12](=[O:21])[C:13]1[CH:18]=[C:17]([Cl:19])[CH:16]=[C:15]([Cl:20])[CH:14]=1)([CH3:10])[C:3]([CH2:5][O:6]C(=O)C)=[O:4].C(=O)([O-])[O-].[K+].[K+]>CO>[CH3:10][C:2]([NH:11][C:12](=[O:21])[C:13]1[CH:18]=[C:17]([Cl:19])[CH:16]=[C:15]([Cl:20])[CH:14]=1)([CH3:1])[C:3]([CH2:5][OH:6])=[O:4]

참가 물질

4

반응물 2

HCID 11430Potassium CarbonateHCID 53897658HCID 53897658, 화합물

생성물 1

HCID 54349857HCID 54349857, 화합물수율 98%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

N-(1',1'-dimethyl-3'-acetoxyacetonyl)-3,5-dichlorobenzamide (5.0 gm, 0.15 m) was treated with potassium carbonate (0.21 gm, 0.0015 m) in 250 ml methanol at room temperature for 12 hours. The methanol was removed by a vacuum, the residue was taken up in ether and washed successively with saturated sodium bicarbonate, water and brine. Drying of the ether solution followed by removing the solvent yielded 4.0 gm (98%) of pure product.

후처리

  1. customThe methanol was removed by a vacuum
  2. washwashed successively with saturated sodium bicarbonate, water and brine
  3. dry with materialDrying of the ether solution
  4. customby removing the solvent

출처 및 근거

ORD 기록
ord-007253616b184568b6a3b6c3cad2d9d0
출처 데이터셋
uspto-grants-1997_05
특허 번호
US05629346

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