1,2-Dichloroethane → tert-butyl N-[1-[3-[(2-bromo-1,3-thiazole-4-carbonyl)amino]-4-pyridinyl]piperidin-3-yl]carbamate

HRID 178082

반응식

HRID 178082 반응식
[Br:22][c:23]1[s:24][cH:25][c:26]([C:28](=[O:29])[OH:30])[n:27]1.[CH2:31]([Cl:32])[CH2:33][Cl:34].[CH3:40][CH2:41][O:42][C:43]([CH3:44])=[O:45].[NH2:1][c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1[N:8]1[CH2:9][CH:10]([NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:11][CH2:12][CH2:13]1.[O:35]=[CH:36][N:37]([CH3:38])[CH3:39]>>[NH:1]([c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1[N:8]1[CH2:9][CH:10]([NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:11][CH2:12][CH2:13]1)[C:28]([c:26]1[cH:25][s:24][c:23]([Br:22])[n:27]1)=[O:29]

참가 물질

6

반응물 5

HCID 111,2-DichloroethaneHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 27632092-Bromo-1,3-thiazole-4-carboxylic acidHCID 67130164Tert-butyl 1-(3-aminopyridin-4-yl)piperidin-3-ylcarbamate

생성물 1

HCID 67501061tert-butyl N-[1-[3-[(2-bromo-1,3-thiazole-4-carbonyl)amino]-4-pyridinyl]piperidin-3-yl]carbamate

출처 및 근거

ORD 기록
ord-595ec4d2e5234d05b1f34928114088c1
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

연결된 노트

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