Dichloromethane → HCID 19047584, 화합물

HRID 1780879노트

반응식

HRID 1780879 반응식
[O:1]1[CH:5]=[CH:4][C:3]([C:6](=O)[CH2:7]C)=[CH:2]1.[C:10](=[O:13])([O-])[O-].[K+].[K+].[CH2:16](Cl)Cl>O.C1(C)C=CC(S(O)(=O)=O)=CC=1>[O:1]1[CH:5]=[CH:4][C:3]([C:6]([O:13][CH2:10][CH3:16])=[CH2:7])=[CH:2]1

참가 물질

5

반응물 3

HCID 6344DichloromethaneHCID 11430Potassium CarbonateHCID 150538531-(3-Furanyl)-1-propanone

생성물 1

HCID 19047584HCID 19047584, 화합물수율 29%

시약·촉매·용매 1

HCID 521998p-Toluenesulfonic acid monohydrate촉매

실험 절차

To a stirring mixture of 1-(3-furyl)-1-propanone (6.75 g, 0.0612 mol) in 150 mL of methylene chloride was added TEOF (13.2 mL, 0.079 mol) with stirring followed by 100 mg of p-toluenesulfonic acid monohydrate and the resulting mixture was stirred for 126 h. Potassium carbonate (2 g) was added to the above reaction mixture, stirred for 10 min, filtered, and concentrated in vacuo. The residue was distilled (35 mm, 82°-85° C.) to afford 2.5 g (29%) of 1-(3-furyl)-1-ethoxy-ethylene (Formula III: R3 =R4 =H; R5 =CH3CH2O;R6 =3-furanyl), as a clear oil.

후처리

  1. additionwas added TEOF (13.2 mL, 0.079 mol)
  2. stirringthe resulting mixture was stirred for 126 h
  3. stirringstirred for 10 min
  4. filtrationfiltered
  5. concentrationconcentrated in vacuo
  6. distillationThe residue was distilled (35 mm, 82°-85° C.)

출처 및 근거

ORD 기록
ord-f5edbda3a9114165a281273d70aa98c6
출처 데이터셋
uspto-grants-1997_05
특허 번호
US05631264

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