Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chlorine → 1,2-Benzisothiazol-3(2H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chlorine | HCID 24526 | — |
| 반응물 | Sulfuryl chloride | HCID 24648 | — |
| 반응물 | 2-(Methylthio)benzaldehyde oxime | HCID 786757 | — |
| 용매 | Chlorobenzene | HCID 7964 | — |
| 생성물 | 1,2-Benzisothiazol-3(2H)-one | HCID 17520 | 91.1% |
반응 단계
From the monochlorobenzene layer obtained by the same procedures as in Example 1, 2-(methylthio)benzaldehyde oxime was isolated in the same manner as in Example 2. 39.7 g of the oxime isolated was dissolved in 150 g of monochlorobenzene. Then, the oxime was cyclized in the same manner as in Example 1 except that chlorine was changed to 35.3 g (0.26 mol) of sulfuryl chloride. As a result, 32.7 g of 1,2-benzisothiazol-3-one was obtained. The yield against 2-(methylthio)benzaldehyde oxime was 91%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05633384 |
| 출처 데이터셋 | uspto-grants-1997_05 |
| ORD ID | ord-8e36c12d6bee48f7b869e675e19ea709 |
| 출처 메모 | uspto-grants-1997_05 |