Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(Chloromethyl)-2-fluoro-3,4-dimethoxybenzene → 2-Fluoro-3,4-dimethoxybenzyl acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(Chloromethyl)-2-fluoro-3,4-dimethoxybenzene | HCID 237411 | — |
| 반응물 | Potassium Acetate | HCID 517044 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-Fluoro-3,4-dimethoxybenzyl acetate | HCID 53689459 | — |
반응 단계
5.5 g of α-chloro-2-fluoro-3,4-dimethoxytoluene and 4.05 g of potassium acetate are stirred at 80° for 25 hours in 50 ml of dimethylformamide. The reaction mixture is subsequently poured into 150 ml of ice-water and extracted with ether. The ether phases are washed with sodium chloride solution, dried over sodium sulfate and evaporated. 2-fluoro-3,4-dimethoxybenzyl acetate is obtained as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05633371 |
| 출처 데이터셋 | uspto-grants-1997_05 |
| ORD ID | ord-fcb953faf03c4791831ba3eeb3f3b088 |
| 출처 메모 | uspto-grants-1997_05 |