2-Hydroxy-5-(methoxycarbonyl)benzoic acid → Methyl 1-[2-hydroxy-5-(methoxycarbonyl)benzoyl]-4-piperidinecarboxylate

HRID 1782754노트

반응식

HRID 1782754 반응식
[OH:1][C:2]1[CH:10]=[CH:9][C:8]([C:11]([O:13][CH3:14])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=O.Cl.[NH:16]1[CH2:21][CH2:20][CH:19]([C:22]([O:24][CH3:25])=[O:23])[CH2:18][CH2:17]1>>[OH:1][C:2]1[CH:10]=[CH:9][C:8]([C:11]([O:13][CH3:14])=[O:12])=[CH:7][C:3]=1[C:4]([N:16]1[CH2:21][CH2:20][CH:19]([C:22]([O:24][CH3:25])=[O:23])[CH2:18][CH2:17]1)=[O:6]

참가 물질

3

반응물 2

HCID 127170602-Hydroxy-5-(methoxycarbonyl)benzoic acidHCID 187838294-Piperidinecarboxylic acid, methyl ester, hydrochloride (1:1)

생성물 1

HCID 57589141Methyl 1-[2-hydroxy-5-(methoxycarbonyl)benzoyl]-4-piperidinecarboxylate

실험 절차

Methyl 1-[2-hydroxy-5-(methoxycarbonyl)benzoyl]-4-piperidinecarboxylate is prepared in analogy to the process described in Example IX, method 1, from 2-hydroxy-5-carbomethoxybenzoic acid [CAS No. 79128-78-2] and methyl piperidine-4-carboxylate hydrochloride.

출처 및 근거

ORD 기록
ord-5e6bafed4c4c4ef8ab93d67c01b0ad1a
출처 데이터셋
uspto-grants-2009_03
특허 번호
US07498460B2

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