Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2-Bromophenyl)hydrazine → 2-[N'-(2-Bromo-phenyl)-hydrazino]-9-methoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2-Bromophenyl)hydrazine | HCID 85583 | — |
| 반응물 | 2-chloro-9-methoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one | HCID 57591093 | — |
| 생성물 | 2-[N'-(2-Bromo-phenyl)-hydrazino]-9-methoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one | HCID 57591099 | — |
반응 단계
The title compound was prepared from 2-chloro-9-methoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one (4) and (2-bromo-phenyl)-hydrazine as in Example 1 d. 1H-NMR (400 MHz, d6-DMSO at 60° C.) δ 9.19 (br, 1H), 7.66 (brd, 1H), 7.46 (d, 1H), 7.44 (br, 1H), 7.20 (t, 1H), 6.98-6.75 (3H), 6.71 (t, 1H), 6.23 (s, 1H), 3.94 (t, 2H), 3.82 (s, 3H) and 2.93 (t, 2H); MS (ESI) (M+H)+ 413, 415.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07501512B2 |
| 출처 데이터셋 | uspto-grants-2009_03 |
| ORD ID | ord-c16444c92ddc4fdfa9dee910b7189801 |
| 출처 메모 | uspto-grants-2009_03 |