2-Amino-5-chlorobenzenesulphonamide → 7-Chloro-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide

반응식

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[S:9]([NH2:12])(=[O:11])=[O:10].[CH:13]([O-])([O-])OCC>>[Cl:8][C:5]1[CH:6]=[CH:7][C:2]2[NH:1][CH:13]=[N:12][S:9](=[O:11])(=[O:10])[C:3]=2[CH:4]=1

참가 물질

반응물 2

HCID 122955502-Amino-5-chlorobenzenesulphonamide

HCID 53630039Ethylorthoformate

생성물 1

HCID 100362767-Chloro-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide

실험 절차

A mixture of 2-amino-5-chlorobenzenesulphonamide (obtained according to J. Chem. Soc. Perkin I, 1043-1047, 1979) and ethyl orthoformate (40 mL) is heated at boiling for 30 minutes in an open vessel. The volume of the mixture is reduced by half under reduced pressure. The precipitate obtained is collected by filtration, washed with ether and dried.

후처리

temperatureis heated
customThe precipitate obtained
filtrationis collected by filtration
washwashed with ether
customdried

출처 및 근거

ORD 기록: ord-6b717345c1614eb9a2a1a77154c00af2
출처 데이터셋: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07741320B2

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