4-Fluorophenylboronic acid → 5-(4-fluorophenyl)pyrimidine-2-carboxylic Acid
반응식
Br[C:2]1[CH:3]=[N:4][C:5]([C:8]([OH:10])=[O:9])=[N:6][CH:7]=1.[F:11][C:12]1[CH:17]=[CH:16][C:15](B(O)O)=[CH:14][CH:13]=1>>[F:11][C:12]1[CH:17]=[CH:16][C:15]([C:2]2[CH:3]=[N:4][C:5]([C:8]([OH:10])=[O:9])=[N:6][CH:7]=2)=[CH:14][CH:13]=1참가 물질
3
실험 절차
Conducting the operations similar to those of Production Example 14 using 5-bromopyrimidine-2-carboxylic acid and 4-fluorophenylboronic acid, the title compound was obtained as white solid.
출처 및 근거
- ORD 기록
- ord-b274ef78305f4bec9deccbe1812eac39
- 출처 데이터셋
- uspto-grants-2009_03
- 특허 번호
- US07504412B2
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