4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid → N-(3-methylimidazo[1,2-a]pyridin-6-yl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxamide
반응식
[CH3:1][C:2]1[N:6]2[CH:7]=[C:8]([N+:11]([O-])=O)[CH:9]=[CH:10][C:5]2=[N:4][CH:3]=1.[F:14][C:15]([F:32])([F:31])[C:16]1[CH:21]=[CH:20][C:19]([C:22]2[CH:27]=[CH:26][C:25]([C:28](O)=[O:29])=[CH:24][CH:23]=2)=[CH:18][CH:17]=1>>[CH3:1][C:2]1[N:6]2[CH:7]=[C:8]([NH:11][C:28]([C:25]3[CH:24]=[CH:23][C:22]([C:19]4[CH:20]=[CH:21][C:16]([C:15]([F:14])([F:31])[F:32])=[CH:17][CH:18]=4)=[CH:27][CH:26]=3)=[O:29])[CH:9]=[CH:10][C:5]2=[N:4][CH:3]=1참가 물질
3
실험 절차
Conducting the operations similar to those of Example 1 using 3-methyl-6-nitroimidazo[1,2-a]pyridine and 4′-(trifluoromethyl)-[1,1′-biphenyl]-4-carboxylic acid, the title compound was obtained as white solid.
출처 및 근거
- ORD 기록
- ord-aa58958213264d5881885ba6b7704af5
- 출처 데이터셋
- uspto-grants-2009_03