(3-Nitrophenyl)urea → (3-Aminophenyl)urea

HRID 1785308노트

반응식

HRID 1785308 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([NH:10][C:11]([NH2:13])=[O:12])[CH:7]=[CH:8][CH:9]=1)([O-])=O>[Pd].CO>[NH2:1][C:4]1[CH:5]=[C:6]([NH:10][C:11]([NH2:13])=[O:12])[CH:7]=[CH:8][CH:9]=1

참가 물질

4

반응물 1

HCID 3400496(3-Nitrophenyl)urea

생성물 1

HCID 108806(3-Aminophenyl)urea

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

A solution of N-(3-nitrophenyl)-urea (1.0 g, 5-5 mmol) and methanol (40 mL) was treated with 10% Pd/C (250 mg) and placed under H2 (45 psi) for 2 h. The mixture was then filtered through celite and concentrated to afford N-(3-aminophenyl)-urea (828 mg, 5.5 mmol).

후처리

  1. filtrationThe mixture was then filtered through celite
  2. concentrationconcentrated

출처 및 근거

ORD 기록
ord-27525ecb4b4a4ca99e802618e7fc8b19
출처 데이터셋
uspto-grants-2009_03
특허 번호
US07504410B2

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