3-(2,4'-Dichlorobenzhydryloxy)azetidine hydrochloride → 3-[2-(Trifluoromethyl)-4'-chlorobenzhydryloxy]azetidine hydrochloride
반응식
C([N:14]1[CH2:17][CH:16]([O:18][CH:19]([C:30]2[CH:35]=[CH:34][C:33]([Cl:36])=[CH:32][CH:31]=2)[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[C:26]([F:29])([F:28])[F:27])[CH2:15]1)(C1C=CC=CC=1)C1C=CC=CC=1.Cl.ClC1C=CC=CC=1C(OC1CNC1)C1C=CC(Cl)=CC=1>>[ClH:36].[F:29][C:26]([F:27])([F:28])[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=1[CH:19]([O:18][CH:16]1[CH2:17][NH:14][CH2:15]1)[C:30]1[CH:35]=[CH:34][C:33]([Cl:36])=[CH:32][CH:31]=1참가 물질
3
실험 절차
This material was prepared from 1-benzhydryl-3-[2-(trifluoromethyl)-4′-chlorobenzhydryloxy]azetidine (97) (25.6 mmol) using the procedure described for compound (9) (8.2 g, 85%).
출처 및 근거
- ORD 기록
- ord-d5a456fbf37b41c096141755c7d05d50
- 출처 데이터셋
- uspto-grants-2009_03
- 특허 번호
- US07504522B2
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