Isocyanate → 3-[2-(trifluoromethyl)-4'-chlorobenzhydryloxy]-N-[(S)-alpha-methyl-benzyl]azetidine-1-carboxamide
반응식
Cl.[F:2][C:3]([F:24])([F:23])[C:4]1[CH:22]=[CH:21][CH:20]=[CH:19][C:5]=1[CH:6]([O:14][CH:15]1[CH2:18][NH:17][CH2:16]1)[C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][CH:8]=1.[N-:25]=[C:26]=[O:27]>>[F:24][C:3]([F:2])([F:23])[C:4]1[CH:22]=[CH:21][CH:20]=[CH:19][C:5]=1[CH:6]([O:14][CH:15]1[CH2:18][N:17]([C:26]([NH:25][C@@H:6]([CH3:7])[C:5]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:4]=2)=[O:27])[CH2:16]1)[C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][CH:8]=1참가 물질
3
실험 절차
This material was prepared from 3-[2-(trifluoromethyl)-4′-chlorobenzhydryloxy]azetidine hydrochloride (98) and the corresponding isocyanate using the procedure described for compound (10).
출처 및 근거
- ORD 기록
- ord-6b640dd79e454835b4b48cb47c3df42b
- 출처 데이터셋
- uspto-grants-2009_03
- 특허 번호
- US07504522B2
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